The Wishart Node of The Metabolomics Innovation Centre features a comprehensive suite of state-of-the-art equipment for targeted and untargeted metabolomic analysis, including mass spectrometry, NMR, UHPLC, and UV-LC systems.
This instrument is used for LC-MS/MS. Tandem quadrupole and ion trap mass spectrometers are ideal for targeted and quantitative studies. Multiple reaction monitoring (MRM) is used on these instruments to selectively measure specific metabolites and their internal standard, providing absolute quantitation.
Advanced tandem quadrupole and ion trap mass spectrometer featuring enhanced sensitivity and speed. This instrument provides superior performance for targeted quantitative analyses with Multiple Reaction Monitoring (MRM) capabilities for precise metabolite quantification.
High-performance liquid chromatography is one of the most powerful and versatile analytical techniques for separation, identification, and quantification of metabolites present in different biofluids and plant materials. Detectors coupled to HPLC include ultra-violet (UV), fluorescence, and evaporative light scattering detector (ELSD).
Gas chromatography-mass spectrometry is a very powerful technique and has been regarded as the gold standard for analyzing lipids, drug metabolites and environmental analysis for many years. The identification is based on both retention time and mass spectrum (compound's specific fragmentation pattern).
Liquid chromatography-mass spectrometry instrumentation capable of tandem quadrupole, ion trap analysis for both targeted and untargeted studies. This powerful chemical identification technique combines physical separation via liquid chromatography with mass spectrometry for mass analysis, providing high sensitivity and selectivity.
Nuclear magnetic resonance is a powerful spectroscopic technique that measures the absorption of radio-frequency radiation by different nuclei when placed under a strong magnetic field. NMR is unique as one of the few non-destructive methods for analyzing 3D structure and molecular dynamics.
Nitrogen gas generators produce high purity nitrogen from compressed air. Housing the generator in the Wishart Node's lab eliminates the need to rely on outside companies to deliver nitrogen, ensuring consistent supply for all analytical instruments.
Ultra-high performance liquid chromatography systems feature a design focused on uptime, robustness and reliability. Multiple detection options make performance and flexibility possible. These systems are ideal for method development or high-throughput analyses with exceptional accuracy and precision.
Inductively coupled plasma mass spectrometry (ICP-MS) is used for quantitative metallomics. We routinely identify and quantify 20-40 metal ions in a wide variety of biological matrices, providing essential data for understanding metal-based biological processes and toxicology studies.
Our team of experts is here to help you select the most appropriate instrument and analysis type for your specific research project.